Nicolas Nørager prepares PhD looking at the dynamics between central venous pressure and intracranial pressure

In the upcoming PhD project, we aim to explore the crucial relationship between venous pressure (CVP) regulation and intracranial pressure (ICP) management. Our focus is particularly on understanding the role of central venous pressure in influencing cerebral venous drainage and ICP.

By investigating innovative techniques to reduce CVP, we aim to enhance venous outflow from the brain, thereby lowering ICP in conditions such as traumatic brain injury, intracerebral hemorrhage, and other critical neurosurgical disorders. This research seeks to develop novel approaches for reducing ICP in the acute setting. One of the key techniques under investigation is Intrathoracic Pressure Regulation (IPR), which uses controlled negative pressure during expiration to optimize venous return and improve ICP management.

Through this research, we strive to deepen our understanding of venous contributions to intracranial dynamics and to develop safer, more effective strategies for controlling elevated ICP, with the ultimate goal of improving outcomes for the patients.